PHP 5.3.3 or later. It is recommended to use PHP 5.4.0 or later to get access to the latest mysqlnd features.
The mysqlnd_uh user handler plugin supports all PHP applications and all available PHP MySQL extensions (mysqli, mysql, PDO_MYSQL). The PHP MySQL extension must be configured to use mysqlnd in order to be able to use the mysqlnd_uh plugin for mysqlnd.
The alpha versions makes use of some mysqli features. You must enable mysqli to compile the plugin. This requirement may be removed in the future. Note, that this requirement does not restrict you to use the plugin only with mysqli. You can use the plugin to monitor mysql, mysqli and PDO_MYSQL.